Japanese Voices:
| Amuro Ray | Toru Furuya |
| Bright Noa | Hirotaka Suzuoki |
| Ryu Jose | Shozo Iizuka |
| Kai Shiden | Toshio Furukawa |
| Hyato Kobayashi | Kiyonobu Suzuki |
| Mirai Yashima | Fuyumi Shiraishi |
| Sayla Mass | Yo Inoue |
| Fraw Bow | Rumika Ukai |
| Garma Zabi | Katsuji Mori |
| Dewgin Zabi | Hidekatsu Shibata |
| Dozul Zabi | Tessa Genda |
| Kycilia Zabi | Mami Koyama |
| Gihren Zabi | Banjo Ginga |
| Matilda Ajan | Heiko Toda |
| Tem Ray | Motomu Kiyokawa |
| Marka Clan | Jun Fukuyama |
| Oscar Dublin | Hazunari Tanaka |
| Omur Fang | Masaya Takasuka |
| Commandant Wakkein | Toru Inada |
| Lt. Reed | Kazuhiko Kishino |
| Ramba Ral | Masahi Hirose |
| Hamon Ral | Yumi Nakaya |
| Akoss | Kihachiro Uemura |
| Cozun | Yutaka Royama |
| Icelina Eschonbach | Shiho Nagoshi |
| Mayor Eschonbach | Katsunosuke Hori |
| Slender | Eiji Yanagisawa |
| Gene | Junpei Morita |
| Gadem | Taimei Suzuki |
| Krampe | Hiroshi Matsumoto |
| Guevil | Tomohisa Rsou |
| Fraw's Mother | Mizuho Tushima |
| Amuro's Mother | Saori Hato |
| Char Aznable | Shuichi Ikeda |
| Lt. Woody | Masaaki Ukabe |
| Admiral Revil | Katsunosuke Hori |
| Elran | Kousei Yagi |
| M'Quve | Masahiko Tanaka |
| Job John | Daisuke Kishio |
| Sleggar Law | Makio Inoue |
| Miharu Ratokie | Satomi Majima |
| Mulligan | Bunkou Ogata |
| Cameron Bloom | Hiroshi Isobe |
| Tianem | Takao Ooyama |
| Lalah Sune | Keiko Han |
| Flanagan | Mitsuaki Hoshino |
| Tamura | Jun Ishimaru |
| Narrator | Ichiro Nagai |
English Voices:
| Amuro Ray | Brad Swaile |
| Bright Noa | Chris Kalhoon |
| Ryu Jose | Ward Perry |
| Kai Shiden | Richard Ian Cox |
| Hyato Kobayashi | Matt Smith |
| Mirai Yashima | Cathy Weseluck |
| Sayla Mass | Alaina Burnett |
| Fraw Bow | Kristie Marsden |
| Garma Zabi | Brian Dobson |
| Dewgin Zabi | Eric Schneider |
| Dozul Zabi | French Tickner |
| Kycilia Zabi | Michelle Porter |
| Gihren Zabi | Hiro Kanagawa |
| Matilda Ajan | Sylvia Zaradic |
| Tem Ray | Trevor Devall |
| Marka Clan | Tyronne L'Hirondelle |
| Oscar Dublin | Brendan Beiser |
| Omur Fang | Glenn Hopkins |
| Commandant Wakkein | Ted Cole |
| Lt. Reed | Scott McNeil |
| Ramba Ral | John Payne |
| Hamon Ral | Lenore Zann |
| Akoss | |
| Cozun | Ron Halder |
| Icelina Eschonbach | Marjorie Malpass |
| Mayor Eschonbach | |
| Slender | |
| Gene | Ted Cole |
| Gadem | Michael Dobson |
| Krampe | |
| Guevil | |
| Fraw's Mother | |
| Amuro's Mother | Lisa Ann Beley |
| Char Aznable | Michael Kopsa |
| Lt. Woody | Kirby Morrow |
| Admiral Revil | Michael Dobson |
| Elran | Ward Perry |
| M'Quve | Michael Benyaer |
| Job John | |
| Sleggar Law | Bill Mondy |
| Miharu Ratokie | Kelly Sheridan |
| Mulligan | Ward Perry |
| Cameron Bloom | David Mackay |
| Tianem | Ward Perry |
| Lalah Sune | Willow Johnson |
| Flanagan | Brian Drummond |
| Tamura | |
| Narrator | Ross Douglas |